According to WHO statistics, less than 10% demand of organs for transplantation is fulfilled, a huge research and supply-demand gap exists in this area. Clinical cryopreservation of tissues and organs from donors for transplantation to recipients is essential for conserving organs. Effective cryopreservation strategy helps in slowing down the cellular functions and preserving the physiological and biochemical structures of the organs. Commonly used cryopreservation strategies are optimal for short term storage. In case recipients are not immediately available for transplant, we need to identify the most efficient strategy for organ storage in organ banks for transplantation later.